Two screening tests for dental materials are described one test is an in vitro test using cell culture to determine the general cytotoxic effect of a material cell material contact is obtained by means of millipore filters and changes in enzyme activity of the cells are used as criteria for cell response the second test is an in vivo test to determine the local initial tissue response to a . Methods a mechano regulation algorithm was firstly used to simulate the tissue differentiation around a dental implant during the short term bone healing then the result was used as the initial state of the bone remodeling model to simulate the long term healing of the bones the algorithm was implemented by a 3d finite element model results the current hybrid model reproduced several . A screening method is a process that extracts isolates and identifies a compound or group of components in a sample with the minimum number of steps and the least manipulation of the sample more basically a screening method is a simple measurement providing a yes no response this article examines the interest in applying screening methods from several points of view namely the . Classification of screening methods in material selection 21 cost per unit property method since cost is so important in selecting materials it is logical to consider it at the start of material selection process generally a target cost is set to remove the materials that are very expensive so the final choice is a trade off between cost and performance it can be the most useful . Tissue material interface for dental applications those contacting soft tissues in the mouth those contacting hard tissues in the mouth those affecting the vitality of pulp those affecting root canal filling eg monomers in denture base materials allergic reactions to alloys containing nickel phosphoric acid used as an etchant for enamel mercury in dental amalgam side effects to
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