Download citation transcranial direct current stimulation tdcs emerging uses safety and neurobiological effects transcranial brain stimulation has received an increased interest among the . In particular transcranial direct current stimulation tdcs has been widely explored for its clinical efficacy safety painlessness portability ease of application low cost well tolerated among patients and positive clinical results seen within a few weeks. Transcranial direct current stimulation tdcs is a non invasive brain stimulation method used to modulate cortical excitability through the application of a weak electric current via anodal and cathodal surface electrodes harris love and cohen 2006 nitsche and fregni 2007 tdcs generally produces polarity specific subthreshold modulation of resting membrane potentials nitsche et al 2008. Transcranial direct current stimulation tdcs is a form of neuromodulation that uses constant low direct current delivered via electrodes on the head it was originally developed to help patients with brain injuries or psychiatric conditions like major depressive disorderit can be contrasted with cranial electrotherapy stimulation which generally uses alternating current the same way. Transcranial direct current stimulation tdcs refers to a non invasive brain stimulation technique that uses electrical current to influence the activity of the brains cerebral cortex the idea behind it is that by increasing or decreasing the activity of specific brain regions certain brain functions could be enhanced or suppressed if true this could open up a number of new and